|
KMID : 1007520140230061987
|
|
Food Science and Biotechnology
2014 Volume.23 No. 6 p.1987 ~ p.1996
|
|
|
Evaluation of Synurus deltoides for Antioxidant, Antimicrobial, and Anti-proliferative Activities Using In vitro Assays
|
|
Md. Abul Hasnat
Mehnaz Pervin
Jang Yong-Chang
Kim Young-Ock
Park Soo-jin
Kim Jong-Moon
Lim Ji-Hong
Lim Beong-Ou
|
|
|
Abstract
|
|
|
|
The antioxidant, antimicrobial, and antiproliferative activities of water and ethanol extracts from leaves of Synurus deltoides (SD) were investigated. Extracts showed strong reductive powers, nitrite-scavenging activities, DPPH, ABTS, hydroxyl, and superoxide radical scavenging activities, and DNA damage prevention activities. SD extracts also showed strong cellular antioxidant activities in a dosedependent manner with IC50 values of 0.93 and 0.65 mg/ mL for water and ethanol extracts, respectively. Antimicrobial activities were evaluated against 4 microorganisms. SD extracts showed high inhibitory activities against Pseudomonas aeruginosa and Staphylococcus aureus. The anti-proliferative activity was dose-dependent against human colon adenocarcinoma (HT-29) and mouse rectum carcinoma cells (CMT-93). In addition, HPLC analyses of SD leaf extracts revealed the presence of different phenolic compounds. SD can be considered as a source of functional foods and pharmaceuticals.
|
|
|
KEYWORD
|
|
|
Synurus deltoides, phenol, antioxidant, antimicrobial, anti-proliferative
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|